![]() ![]() In vitro and in vivo studies with tetra-hydro-jasmonic acid (LR2412) reveal its potential to correct signs of skin ageing. La Roche-Posay Scientific Dossier data on file.Improvement of naturally aged skin with vitamin A (retinol). A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet radiation. Murray JC, Burch JA, Streilen RD, et al.Topically applied vitamin C enhances the mRNA level of collagens I and III, their processing enzymes and tissue inhibitor matrix metalloproteinase 1 in the human dermis. Nusgens BV, Humbert P, Rougier, A, et al. ![]() ![]() XXII International Pigment Cell Conference, Singapore 2014. Evaluation and effectiveness of a photoprotective composition sunscreen) on subjects of skin of color. Halder R, Rodney I., Munhutu M., et al.Non-invasive short-term assessment of retinoids effects on human skin in vivo using multiphoton microscopy. Tancrède-Bohin E, Baldeweck T, Decencière E, Brizion S, Victorin S, Parent N, Faugere J, Souverain L, Bagot M, Pena AM.Assessment of aging of the human skin by in vivo ultrasonic imaging. de Rigal J, Escof er C, Querleux B, Faivre B, Agache P, Lévêque JL.Lévêque JL1, Querleux B SkinChip, a new tool for investigating the skin surface in vivo.85-96 Verschoore M., Liu Wei editors people’s Medical Publishing House, Beijing. Basic Science for Modern CosmeticDermatologyp. Non invasive methods and imaging techniques for investigating the skin in vivo.Consequences of urban pollution upon skin status. Lefebvre MA, Pham DM, Boussouira B et al.Evaluation of the impact of urban pollution on the quality of skin: a multicentre study in Mexico. Lefebvre MA, Pham DM, Boussouira B, et al.Pollution and skin: from epidemiological and mechanical studies to clinical implications. Cigarette smoking and its influence on skin aging. Skin Aging Atlas, Vols I (Caucasian type), II (Asian type), III (African American type). Dermal contribution to UVA-induced oxidative stress in skin. Cutaneous aging: Chronological versus photo-aging. Nielsen are full-time employees of L’Oréal Research & Innovation. A large range of carefully composed combinations of evidence-based ingredients can now be used for preventing or reversing troublesome concerns about the deterio- ration of the facial look and its related aged skin appearance. Mild exfoliative products that smooth coarse or rough skin can prompt a faster epidermal turnover. These obviously make sun avoidance and protection by broad spectrum sunscreens with strong absorption in the UVA range a primary daily care, especially when coupled with antioxidants. Sun and associated oxidative stress are clearly causative factors in premature altering of the facial appearance and exposed areas. New strategies using prevention, protection and boosting skin metabolism have been devised to test new evidence-based ingredients for skin antiaging bene ts. Skin aging status and appearance can thus be objectively assessed to provide optimal answers to huge demand for skin anti-aging options for all skin types. Advances in methods for quantitative and reproducible evaluation of aging signs by clinicians, trained individuals, and panelists have resulted from outstanding progress in imaging techniques with high resolution level and software for observing, recording, and collecting data up to the ultrastructural level.
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